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2014
Causes of Variation in Bcg Vaccine Efficacy: Examining Evidence from the Bcg Revac Cluster Randomized Trial to Explore the Masking and the Blocking Hypotheses
Barreto ML, Pilger D, Pereira SM, Genser B, Cruz AA, Cunha SS, Sant'Anna C, Hijjar MA, Ichihara MY, Rodrigues LC.
Vaccine. 2014;32(30):3759-3764
DOI: 10.1016/j.vaccine.2014.05.042
Community-Based Efforts to Promote Physical Activity: A Systematic Review of Interventions Considering Mode of Delivery, Study Quality and Population Subgroups
Bock C, Jarczok MN, Litaker D.
J Sci Med Sport. 2014;17(3):276-282
DOI: 10.1016/j.jsams.2013.04.009
On-Call Service of Neurosurgeons in Germany: Organization, Use of Communication Services, and Personal Acceptance of Modern Technologies
Brenke C, Lassel EA, Terris D, Kurt A, Schmieder K, Schoenberg SO, Weisser G.
J Neurol Surg A Cent Eur Neurosurg. 2014;75(3):217-223
Relation of Genetic Profile and Novel Circulating Biomarkers with Coronary Plaque Phenotype as Determined by Intravascular Ultrasound: Rationale and Design of the Atheroremo-Ivus Study
de Boer SP, Cheng JM, Garcia-Garcia HM, Oemrawsingh RM, van Geuns RJ, Regar E, Zijlstra F, Laaksonen R, Halperin E, Kleber ME, Koenig W, Boersma E, Serruys PW.
EuroIntervention. 2014;10(8):953-960
DOI: 10.4244/eijy13m08_01
Substance Use among Elite Adolescent Athletes: Findings from the Goal Study
Diehl K, Thiel A, Zipfel S, Mayer J, Schneider S.
Scand J Med Sci Sports. 2014;24(1):250-258
DOI: 10.1111/j.1600-0838.2012.01472.x
Possibilities to Support Elite Adolescent Athletes in Improving Performance: Results from a Qualitative Content Analysis
Diehl K, Thielmann I, Thiel A, Mayer J, Zipfel S, Schneider S.
Science & Sports. 2014;29(6):e115-e125
DOI: 10.1016/j.scispo.2014.03.004
Increased Soluble St2 Predicts Long-Term Mortality in Patients with Stable Coronary Artery Disease: Results from the Ludwigshafen Risk and Cardiovascular Health Study
Dieplinger B, Egger M, Haltmayer M, Kleber ME, Scharnagl H, Silbernagel G, de Boer RA, März W, Mueller T.
Clin Chem. 2014;60(3):530-540
DOI: 10.1373/clinchem.2013.209858
Preschools' Friendliness toward Physical Activity: Item Battery and Two Scores Developed by Mixed Methods
Dörr CS, Bock C, Fischer JE, De Bock F.
Am J Prev Med. 2014;46(6):593-604
DOI: 10.1016/j.amepre.2014.01.015
Dietary Counselling for Cardiovascular Disease Prevention in Primary Care Settings: Results from a German Physician Survey
Görig T, Mayer M, Bock C, Diehl K, Hilger J, Herr RM, Schneider S.
Fam Pract. 2014;31(3):325-332
Copper, Ceruloplasmin, and Long-Term Cardiovascular and Total Mortality (the Ludwigshafen Risk and Cardiovascular Health Study)
Grammer TB, Kleber ME, Silbernagel G, Pilz S, Scharnagl H, Lerchbaum E, Tomaschitz A, Koenig W, März W.
Free Radic Res. 2014;48(6):706-715
DOI: 10.3109/10715762.2014.901510
Hemoglobin, Iron Metabolism and Angiographic Coronary Artery Disease (the Ludwigshafen Risk and Cardiovascular Health Study)
Grammer TB, Kleber ME, Silbernagel G, Pilz S, Scharnagl H, Tomaschitz A, Konig W, März W.
Atherosclerosis. 2014;236(2):292-300
DOI: 10.1016/j.atherosclerosis.2014.07.002
Plant Sterols and Plant Stanols in the Management of Dyslipidaemia and Prevention of Cardiovascular Disease
Gylling H, Plat J, Turley S, Ginsberg HN, Ellegard L, Jessup W, Jones PJ, Lutjohann D, März W, Masana L, Silbernagel G, Staels B, Boren J, Catapano AL, De Backer G, Deanfield J, Descamps OS, Kovanen PT, Riccardi G, Tokgozoglu L, Chapman MJ.
Atherosclerosis. 2014;232(2):346-360
DOI: 10.1016/j.atherosclerosis.2013.11.043
Fish Consumption, Sleep, Daily Functioning, and Heart Rate Variability
Hansen AL, Dahl L, Olson G, Thornton D, Graff IE, Froyland L, Thayer JF, Pallesen S.
J Clin Sleep Med. 2014;10(5):567-575
DOI: 10.5664/jcsm.3714
Psychometric Properties of a German Organizational Justice Questionnaire (G-Ojq) and Its Association with Self-Rated Health: Findings from the Mannheim Industrial Cohort Studies (Mics)
Herr RM, Li J, Bosch JA, Schmidt B, DeJoy DM, Fischer JE, Loerbroks A.
Int Arch Occup Environ Health. 2014;87(1):85-93
DOI: 10.1007/s00420-012-0839-4
A Systematic Review of Vitamin D Status in Populations Worldwide
Hilger J, Friedel A, Herr R, Rausch T, Roos F, Wahl DA, Pierroz DD, Weber P, Hoffmann K.
Br J Nutr. 2014;111(1):23-45
DOI: 10.1017/s0007114513001840
Does Maternal Underweight Prior to Conception Influence Pregnancy Risks and Outcome?
Hoellen F, Hornemann A, Haertel C, Reh A, Rody A, Schneider S, Tuschy B, Bohlmann MK.
In Vivo. 2014;28(6):1165-1170
URL: https://www.ncbi.nlm.nih.gov/pubmed/25398817
Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-up Implicates Endothelial Stxbp5 and Stx2
Huang J, Huffman JE, Yamakuchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Tregouet DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, Johnson AD, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley BM, Moore JH, Williams FM, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler GH, Navis GJ, Destefano A, Wright AF, Chen MH, de Craen AJ, Worrall BB, Rudnicka AR, Rumley A, Bookman EB, Psaty BM, Chen F, Keene KL, Franco OH, Bohm BO, Uitterlinden AG, Carter AM, Jukema JW, Sattar N, Bis JC, Ikram MA, Sale MM, McKnight B, Fornage M, Ford I, Taylor K, Slagboom PE, McArdle WL, Hsu FC, Franco-Cereceda A, Goodall AH, Yanek LR, Furie KL, Cushman M, Hofman A, Witteman JC, Folsom AR, Basu S, Matijevic N, van Gilst WH, Wilson JF, Westendorp RG, Kathiresan S, Reilly MP, Tracy RP, Polasek O, Winkelmann BR, Grant PJ, Hillege HL, Cambien F, Stott DJ, Lowe GD, Spector TD, Meigs JB, Marz W, Eriksson P, Becker LC, Morange PE, Soranzo N, Williams SM, Hayward C, van der Harst P, Hamsten A, Lowenstein CJ, Strachan DP, O'Donnell CJ.
Arterioscler Thromb Vasc Biol. 2014;34(5):1093-1101
DOI: 10.1161/atvbaha.113.302088
Lower Heart Rate Variability Predicts Increased Level of C-Reactive Protein 4 Years Later in Healthy, Nonsmoking Adults
Jarczok MN, Koenig J, Mauss D, Fischer JE, Thayer JF.
J Intern Med. 2014;276(6):667-671
DOI: 10.1111/joim.12295
Two-Week Test-Retest Stability of the Cold Pressor Task Procedure at Two Different Temperatures as a Measure of Pain Threshold and Tolerance
Koenig J, Jarczok MN, Ellis RJ, Bach C, Thayer JF, Hillecke TK.
Pain Pract. 2014;14(3):E126-135
DOI: 10.1111/papr.12142
Heart Rate Variability and Experimentally Induced Pain in Healthy Adults: A Systematic Review
Koenig J, Jarczok MN, Ellis RJ, Hillecke TK, Thayer JF.
Eur J Pain. 2014;18(3):301-314
DOI: 10.1002/j.1532-2149.2013.00379.x
Body Mass Index Is Related to Autonomic Nervous System Activity as Measured by Heart Rate Variability--a Replication Using Short Term Measurements
Koenig J, Jarczok MN, Warth M, Ellis RJ, Bach C, Hillecke TK, Thayer JF.
J Nutr Health Aging. 2014;18(3):300-302
DOI: 10.1007/s12603-014-0022-6
The Quick Inventory of Pain Symptoms (Qips): A First Evaluation on Concurrent Validity and Sex Differences.
Koenig J, Jarczok MN, Warth M, Hillecke TK, Thayer JF.
SAGE Open. 2014;4(4):1-7
Heart Rate Variability and Swimming
Koenig J, Jarczok MN, Wasner M, Hillecke TK, Thayer JF.
Sports Med. 2014;44(10):1377-1391
DOI: 10.1007/s40279-014-0211-9
C-Reactive Protein Predicts Mortality in Patients Referred for Coronary Angiography and Symptoms of Heart Failure with Preserved Ejection Fraction
Koller L, Kleber M, Goliasch G, Sulzgruber P, Scharnagl H, Silbernagel G, Grammer T, Delgado G, Tomaschitz A, Pilz S, März W, Niessner A.
Eur J Heart Fail. 2014;16(7):758-766
DOI: 10.1002/ejhf.104
Comparison of Cost-Effectiveness of Anticoagulation with Dabigatran, Rivaroxaban and Apixaban in Patients with Non-Valvular Atrial Fibrillation across Countries
Krejczy M, Harenberg J, Marx S, Obermann K, Frolich L, Wehling M.
J Thromb Thrombolysis. 2014;37(4):507-523
DOI: 10.1007/s11239-013-0989-6
Association of Mep1a Gene Variants with Insulin Metabolism in Central European Women with Polycystic Ovary Syndrome
Lam UD, Lerchbaum E, Schweighofer N, Trummer O, Eberhard K, Genser B, Pieber TR, Obermayer-Pietsch B.
Gene. 2014;537(2):245-252
DOI: 10.1016/j.gene.2013.12.055
Association of Bone Turnover Markers with Mortality in Women Referred to Coronary Angiography: The Ludwigshafen Risk and Cardiovascular Health (Luric) Study
Lerchbaum E, Schwetz V, Pilz S, Böhm BO, März W.
Osteoporosis International. 2014;25(2):455-465
DOI: 10.1007/s00198-013-2411-9
The Association of Depression and Angina Pectoris across 47 Countries: Findings from the 2002 World Health Survey
Loerbroks A, Bosch JA, Mommersteeg PM, Herr RM, Angerer P, Li J.
Eur J Epidemiol. 2014;29(7):507-515
DOI: 10.1007/s10654-014-9926-z
Primary School Teachers in China: Associations of Organizational Justice and Effort-Reward Imbalance with Burnout and Intentions to Leave the Profession in a Cross-Sectional Sample
Loerbroks A, Meng H, Chen ML, Herr R, Angerer P, Li J.
Int Arch Occup Environ Health. 2014;87(7):695-703
DOI: 10.1007/s00420-013-0912-7
Novel Genetic Markers Associate with Atrial Fibrillation Risk in Europeans and Japanese
Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dorr M, Ozaki K, Smith AV, Muller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kaab S, Mahida S, Kathiresan S, Kubo M, Launer LJ, MacFarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Volker U, Volzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, Marz W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT.
J Am Coll Cardiol. 2014;63(12):1200-1210
DOI: 10.1016/j.jacc.2013.12.015
Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease
Makinen VP, Civelek M, Meng Q, Zhang B, Zhu J, Levian C, Huan T, Segre AV, Ghosh S, Vivar J, Nikpay M, Stewart AF, Nelson CP, Willenborg C, Erdmann J, Blakenberg S, O'Donnell CJ, März W, Laaksonen R, Epstein SE, Kathiresan S, Shah SH, Hazen SL, Reilly MP, Lusis AJ, Samani NJ, Schunkert H, Quertermous T, McPherson R, Yang X, Assimes TL.
PLoS Genet. 2014;10(7):e1004502
DOI: 10.1371/journal.pgen.1004502
Organizational Coherence in Health Care Organizations: Conceptual Guidance to Facilitate Quality Improvement and Organizational Change
McAlearney AS, Terris D, Hardacre J, Spurgeon P, Brown C, Baumgart A, Nystrom ME.
Qual Manag Health Care. 2014;23(4):254-267
DOI: 10.1097/QMH.0000000000000044
Single Nucleotide Variants in the Protein C Pathway and Mortality in Dialysis Patients
Ocak G, Drechsler C, Vossen CY, Vos HL, Rosendaal FR, Reitsma PH, Hoffmann MM, März W, Ouwehand WH, Krediet RT, Boeschoten EW, Dekker FW, Wanner C, Verduijn M.
PLoS One. 2014;9(5):e97251
DOI: 10.1371/journal.pone.0097251
Vaccine-Induced Inflammation Attenuates the Vascular Responses to Mental Stress
Paine NJ, Ring C, Bosch JA, Drayson MT, Aldred S, Veldhuijzen van Zanten JJ.
Int J Psychophysiol. 2014;93(3):340-348
DOI: 10.1016/j.ijpsycho.2014.06.016
Symmetric Dimethylarginine as Predictor of Graft Loss and All-Cause Mortality in Renal Transplant Recipients
Pihlstrom H, Mjoen G, Dahle DO, Pilz S, Midtvedt K, März W, Abedini S, Holme I, Fellstrom B, Jardine A, Holdaas H.
Transplantation. 2014;98(11):1219-1225
DOI: 10.1097/tp.0000000000000205
Neopterin Is Associated with Cardiovascular Events and All-Cause Mortality in Renal Transplant Patients
Pihlstrom H, Mjoen G, März W, Olav Dahle D, Abedini S, Holme I, Fellstrom B, Jardine A, Pilz S, Holdaaas H.
Clin Transplant. 2014;28(1):111-119
DOI: 10.1111/ctr.12285
Associations of Methylarginines and Homoarginine with Diastolic Dysfunction and Cardiovascular Risk Factors in Patients with Preserved Left Ventricular Ejection Fraction
Pilz S, Edelmann F, Meinitzer A, Gelbrich G, Doner U, Dungen HD, Tomaschitz A, Kienreich K, Gaksch M, Duvinage A, Stahrenberg R, Kunde J, Schmidt A, März W, Wachter R, Pieske B.
J Card Fail. 2014;20(12):923-930
DOI: 10.1016/j.cardfail.2014.09.004
Consistent Associations between Measures of Psychological Stress and Cmv Antibody Levels in a Large Occupational Sample
Rector JL, Dowd JB, Loerbroks A, Burns VE, Moss PA, Jarczok MN, Stalder T, Hoffman K, Fischer JE, Bosch JA.
Brain Behav Immun. 2014;38:133-141
DOI: 10.1016/j.bbi.2014.01.012
Association of Myeloperoxidase with Total and Cardiovascular Mortality in Individuals Undergoing Coronary Angiography--the Luric Study
Scharnagl H, Kleber ME, Genser B, Kickmaier S, Renner W, Weihrauch G, Grammer T, Rossmann C, Winkelmann BR, Boehm BO, Sattler W, März W, Malle E.
Int J Cardiol. 2014;174(1):96-105
DOI: 10.1016/j.ijcard.2014.03.168
Association between a Gene Variant near Ataxia Telangiectasia Mutated and Coronary Artery Disease in Men
Schiekofer S, Bobak I, Kleber ME, März W, Rudofsky G, Dugi KA, Schneider JG.
Diab Vasc Dis Res. 2014;11(1):60-63
Incremental Cost Per Quality-Adjusted Life Year Gained? The Need for Alternative Methods to Evaluate Medical Interventions for Ultra-Rare Disorders
Schlander M, Garattini S, Holm S, Kolominsky-Rabas P, Nord E, Persson U, Postma M, Richardson J, Simoens S, Morales OD, Tolley K, Toumi M.
Journal of Comparative Effectiveness Research. 2014;3(4):399-422
DOI: 10.2217/cer.14.34
Occupational Health- Management (BGM): A Strategic Core Business and Economic Necessity
Schmidt B.
Ernährungs Umschau. 2014;61(9):M490-M498
Psychosocial Resources and the Relationship between Transformational Leadership and Employees' Psychological Strain
Schmidt B, Loerbroks A, Herr R, Litaker D, Wilson M, Kastner M, Fischer J.
Work. 2014;49(2):315-324
Associations between Supportive Leadership and Employees Self-Rated Health in an Occupational Sample
Schmidt B, Loerbroks A, Herr RM, Wilson MG, Jarczok MN, Litaker D, Mauss D, Bosch JA, Fischer JE.
Int J Behav Med. 2014;21(5):750-756
DOI: 10.1007/s12529-013-9345-7
Mehr als Nebenwirkungen: Ein theoretisches Modell zu den physischen, psychischen und sozialen Wirkungen des Sports
Schneider S, Diehl K.
Sport-Orthopädie - Sport-Traumatologie - Sports Orthopaedics and Traumatology. 2014;30(1):64-70
DOI: 10.1016/j.orthtr.2013.11.001
Terra Incognita Hausarztpraxis – Tabakentwöhnung in Der Deutschen Primärversorgung
Schneider S, Diehl K, Bock C, Herr R, Mayer M, Lindinger P, Görig T.
SUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice. 2014;60(3):175-187
DOI: 10.1024/0939-5911.a000310
Modifying Health Behavior to Prevent Cardiovascular Diseases: A Nationwide Survey among German Primary Care Physicians
Schneider S, Diehl K, Bock C, Herr RM, Mayer M, Görig T.
Int J Environ Res Public Health. 2014;11(4):4218-4232
Giving Everything for Athletic Success! - Sports-Specific Risk Acceptance of Elite Adolescent Athletes
Schnell A, Mayer J, Diehl K, Zipfel S, Thiel A.
Psychology of Sport and Exercise. 2014;15(2):165-172
DOI: 10.1016/j.psychsport.2013.10.012
Semi-Automated Retinal Vessel Analysis in Nonmydriatic Fundus Photography
Schuster AK, Fischer JE, Vossmerbaeumer U.
Acta Ophthalmol. 2014;92(1):e42-49
DOI: 10.1111/aos.12242
Retinal Vessel Analysis and Heart Rate Variability
Schuster AK, Jarczok MN, Fischer JE, Thayer JF, Vossmerbaeumer U.
Int J Cardiol. 2014;1268-1269
DOI: 10.1016/j.ijcard.2014.07.190
Genome-Wide Association Study on Dimethylarginines Reveals Novel Agxt2 Variants Associated with Heart Rate Variability but Not with Overall Mortality
Seppala I, Kleber ME, Lyytikainen LP, Hernesniemi JA, Makela KM, Oksala N, Laaksonen R, Pilz S, Tomaschitz A, Silbernagel G, Boehm BO, Grammer TB, Koskinen T, Juonala M, Hutri-Kahonen N, Alfthan G, Viikari JS, Kahonen M, Raitakari OT, März W, Meinitzer A, Lehtimaki T.
Eur Heart J. 2014;35(8):524-531
Reply: Intestinal Cholesterol Absorption and Cardiovascular Risk
Silbernagel G, Chapman MJ, Genser B, Kleber ME, Fauler G, Scharnagl H, Grammer TB, Makela KM, Kahonen M, Carmena R, Rietzschel ER, Bruckert E, Deanfield JE, Raitakari OT, Lehtimaki T, März W.
J Am Coll Cardiol. 2014;63(7):696-697
DOI: 10.1016/j.jacc.2013.09.081
Trait Hostility Is Associated with Systemic Inflammation in Married Couples: An Actor-Partner Analysis
Smith TW, Uchino BN, Bosch JA, Kent RG.
Biol Psychol. 2014;102:51-53
DOI: 10.1016/j.biopsycho.2014.07.005
Work Stress and Hair Cortisol Levels among Workers in a Bangladeshi Ready-Made Garment Factory - Results from a Cross-Sectional Study
Steinisch M, Yusuf R, Li J, Stalder T, Bosch JA, Rahman O, Strumpell C, Ashraf H, Fischer JE, Loerbroks A.
Psychoneuroendocrinology. 2014;50:20-27
DOI: 10.1016/j.psyneuen.2014.08.001
Molecular Lipids Identify Cardiovascular Risk and Are Efficiently Lowered by Simvastatin and Pcsk9 Deficiency
Tarasov K, Ekroos K, Suoniemi M, Kauhanen D, Sylvanne T, Hurme R, Gouni-Berthold I, Berthold HK, Kleber ME, Laaksonen R, März W.
J Clin Endocrinol Metab. 2014;99(1):E45-52
DOI: 10.1210/jc.2013-2559
Homoarginine, Kidney Function and Cardiovascular Mortality Risk
Tomaschitz A, Meinitzer A, Pilz S, Rus-Machan J, Genser B, Drechsler C, Grammer T, Krane V, Ritz E, Kleber ME, Pieske B, Kraigher-Krainer E, Fahrleitner-Pammer A, Wanner C, Boehm BO, März W.
Nephrol Dial Transplant. 2014;29(3):663-671
DOI: 10.1093/ndt/gft512
Aldosterone and Parathyroid Hormone Interactions as Mediators of Metabolic and Cardiovascular Disease
Tomaschitz A, Ritz E, Pieske B, Rus-Machan J, Kienreich K, Verheyen N, Gaksch M, Grubler M, Fahrleitner-Pammer A, Mrak P, Toplak H, Kraigher-Krainer E, März W, Pilz S.
Metabolism. 2014;63(1):20-31
DOI: 10.1016/j.metabol.2013.08.016
Ultra-Endurance Exercise: Unanswered Questions in Redox Biology and Immunology
Turner JE, Bennett SJ, Bosch JA, Griffiths HR, Aldred S.
Biochem Soc Trans. 2014;42(4):989-995
DOI: 10.1042/bst20140120
Rudimentary Signs of Immunosenescence in Cytomegalovirus-Seropositive Healthy Young Adults
Turner JE, Campbell JP, Edwards KM, Howarth LJ, Pawelec G, Aldred S, Moss P, Drayson MT, Burns VE, Bosch JA.
Age (Dordr). 2014;36(1):287-297
DOI: 10.1007/s11357-013-9557-4
Health Status and Utilisation of the Healthcare System by Homeless and Non-Homeless People in Vienna
Wagner J, Diehl K, Mutsch L, Löffler W, Burkert N, Freidl W.
Health Soc Care Community. 2014;22(3):300-307
DOI: 10.1111/hsc.12083
Vom Erstspender zum regelmäßigen Spender: Prädiktoren einer erfolgreichen Spenderbindung im Anschluss an die Erstspende
Weidmann C, Schneider S.
Transfusionsmedizin. 2014;4(1):15-22
Monetary Compensation and Blood Donor Return: Results of a Donor Survey in Southwest Germany
Weidmann C, Schneider S, Weck E, Menzel D, Klüter H, Müller-Steinhardt M.
Transfus Med Hemother. 2014;41(4):257-262
DOI: 10.1159/000365525
High Dietary Protein Restores Overreaching Induced Impairments in Leukocyte Trafficking and Reduces the Incidence of Upper Respiratory Tract Infection in Elite Cyclists
Witard OC, Turner JE, Jackman SR, Kies AK, Jeukendrup AE, Bosch JA, Tipton KD.
Brain Behav Immun. 2014;39:211-219